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Teenage boys with hypertrophy of growth have taken weekly injections of 250 mg of testosterone enanthate throughout a yearand seen dramatic improvements in all measures of strength and muscle mass. The effects of this treatment were first documented in 2001. Two years later, however, results of a 12-week randomized trial suggested that the treatment was not superior to placebo and that the most effective response was to maintain treatment at 3mg/kg/day, test e for sale usa.5 In addition, results from a 10-week trial have shown that a single injection of 1,200 mg testosterone enanthate at the time of puberty can significantly affect skeletal muscle mass and strength of adult men, test e for sale usa.6 The latter trial included 17 men (18–20 years of age) who were treated with the 3mg/kg dose and showed that an average increase of more than 80% was seen in both strength and lean mass, test e for sale usa. At the time of the trial, the average testosterone level in the adult male population was 50 ng/dL. At the end of the 10-week trial, the average testosterone level was 56 ng/dL and the results suggested this dose of testosterone may be beneficial to adolescent boys with hypertrophy, testosterone enanthate 250.6 The study and results of the study in males seem to be supported by a study in young girls, in which a placebo arm of the study that was similar to the testosterone arm had no effect (Table ).7 However, the study included a small number of subjects with severe acne with elevated free testosterone: the response was greater for the treated group than for those with mild acne (P<0.0005). A large trial in children followed by a larger trial in adults was conducted using a combination of high-dose testosterone (200–500 mg/kg/day) and a placebo (PV = 2.6).8 There were no statistical differences in the magnitude of change between the two groups at 1 year.9 Another trial on the same topic found that the treatment of a group of young teenagers with acne (aged 12–16 years) and their parents reported that the dose of high-dose testosterone given to all of the patients improved both acne severity and acne response scores.10 In a small trial of 16 boys, 5 of whom were treated with high-dose testosterone enanthate and 6 of whom were treated with placebo enanthate, it was demonstrated that a single injection of 50 mg of testosterone enanthate on the first day of puberty led to a mean increase of more than 40% in the muscle strength/weight ratio, muscle mass, and bone size of these boys, testosterone 250 enanthate.4 One of these patients (age 16) had already begun testosterone and
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